Cells are the basic entities of biological systems. They have particular physical properties, which enable them to navigate their 3D physical environment and fulfill their biological functions. We investigate these physical – mechanical and optical – properties of living cells and tissues using novel photonics and biophysical tools to test their biological importance. Our ultimate goal is the transfer of our findings to medical application in the fields of improved diagnosis of diseases and novel approaches in regenerative medicine.
The mechanical properties of cells can reveal which diseases a patient is suffering from. Researchers at the Max-Planck-Zentrum für Physik und Medizin...
Cells actively sense and respond to a variety of mechanical signals — a process known as mechanosensing. Mechanical cues provided by the extracellular environment can modulate a wide spectrum of cellular events, including cell proliferation, differentiation and protein production. Read More...
Cells define and largely form their surrounding tissues and, in return, receive biochemical and physical cues from them. We are working on resolving this interdependence by quantifying these tissue mechanical properties, correlating them with biological function, investigating their origin and ultimately controlling them. Read More...
The Xenopus spindle is as dense as the surrounding cytoplasm
Developmental Cell 56(7) 967-975 (2021) | Journal
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Max Planck Institute for the Science of Light
D-91058 Erlangen, Germany
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