DLS talk by Laura Waller: “Computational Aberration Correction”
In June we had the honor of welcoming Laura Waller from the University of California, Berkeley within the scope of our Distinguished Lecturer Series (DLS). The professor from the Department of Electrical Engineering and Computer Sciences gave a talk on “Computational Aberration Correction”.
Laura Waller introduced the audience to the fast-growing field of computational imaging, which is transforming cameras and microscopes across many scientific applications. It enables new high-resolution and multi-dimensional measurement capabilities such as 3D, phase, and hyperspectral imaging. Waller presented new space-time algorithms designed to correct aberrations and motion artifacts, even when working with imperfect optical systems. A key approach combines traditional model-based image reconstruction with neural networks to jointly optimize both the inverse problem solver and the data capture strategy.
She further explained how computational imaging involves the joint design of hardware and software, optimizing the entire pipeline from acquisition to reconstruction. Computers can replace bulky and expensive optics by solving computational inverse problems, or enable new imaging modalities by reconstructing invisible quantities or higher-dimensional information from carefully designed measurements. In her talk, Laura Waller described end-to-end learning for the development of new microscopes and space-time algorithms which use computational imaging to enable 3D phase and fluorescence measurements with high resolution and dynamic samples. She illustrated these concepts with examples such as a programmable-illumination microscope featuring an LED array, and a system with patterned illumination achieved with random diffusers (Scotch Tape). Traditional model-based image reconstruction algorithms are based on large-scale nonlinear non-convex optimization; the scientists combine these with neural networks to learn both the image and its algorithmic self-calibration.
DLS brings leading minds in all fields relevant to the science of light to Erlangen. The speakers present their research to a broad audience, enabling scientific exchange.
You can watch Prof. Waller’s talk here: https://www.youtube.com/watch?v=N8kWm30gZiU&list=PL6yOOrXfatatYcdjK_N90smVlWbVLrfj6&index=1
Previous talks are available on our YouTube channel in the DLS playlist.
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