Publications


2021  |  2020  |  2019  |  2018  |  2017  |  2016  |  2015  |  2014  |  2012


2021

Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7

Simon Wisnovsky, Leonhard Möckl, Stacy A. Malaker, Kayvon Pedram, Gaelen T. Hess, Nicholas M. Riley, Melissa A. Gray, Benjamin A. H. Smith, Michael C. Bassik, et al.

Proceedings of the National Academy of Sciences of the United States of America 118(5) e2015024118 (2021) | Journal | PDF


2020

Super-resolution Microscopy with Single Molecules in Biology and Beyond–Essentials, Current Trends, and Future Challenges

Leonhard Möckl, W. E. Moerner

Journal of the American Chemical Society 142(42) 17828-17844 (2020) | Journal | PDF

Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation

Marjoke F. Debets, Omur Y. Tastan, Simon P. Wisnovsky, Stacy A. Malaker, Nikolaos Angelis, Leonhard Möckl, Junwon Choi, Helen Flynn, Lauren J. S. Wagner, et al.

Proceedings of the National Academy of Sciences of the United States of America 117(41) 25293-25301 (2020) | Journal | PDF

From small Beginnings to steep Ascent The Fraunhofer Society

Jürgen Evers, Christiane Herzog, Leonhard Möckl

Chemie in unserer Zeit (2020) | Journal

Supersensitive Multifluorophore RNA-FISH for Early Virus Detection and Flow-FISH by Using Click Chemistry

Nada Raddaoui, Stefano Croce, Florian Geiger, Alexander Borodavka, Leonhard Möckl, Samuele Stazzoni, Bastien Viverge, Christoph Braeuchle, Thomas Frischmuth, et al.

ChemBioChem 21(15) 2214-2218 (2020) | Journal | PDF

The Emerging Role of the Mammalian Glycocalyx in Functional Membrane Organization and Immune System Regulation

Leonhard Möckl

Frontiers in Cell and Developmental Biology 8 253 (2020) | Journal | PDF

Deep learning in single-molecule microscopy: fundamentals, caveats, and recent developments [Invited]

Leonhard Möckl, Anish R. Roy, W. E. Moerner

Biomedical Optics Express 11(3) 1633-1661 (2020) | Journal | PDF

Accurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnet

Leonhard Möckl, Anish R. Roy, Petar N. Petrov, W. E. Moerner

Proceedings of the National Academy of Sciences of the United States of America 117(1) 60-67 (2020) | Journal | PDF


2019

Accurate phase retrieval of complex 3D point spread functions with deep residual neural networks

Leonhard Möckl, Petar N. Petrov, W. E. Moerner

APPLIED PHYSICS LETTERS 115(25) 251106 (2019) | Journal

A Photoswitchable Trivalent Cluster Mannoside to Probe the Effects of Ligand Orientation in Bacterial Adhesion

Guillaume Despras, Leonhard Möckl, Anne Heitmann, Insa Stamer, Christoph Braeuchle, Thisbe K. Lindhorst

ChemBioChem 20(18) 2373-2382 (2019) | Journal

Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx

Leonhard Möckl, Kayvon Pedram, Anish R. Roy, Venkatesh Krishnan, Anna-Karin Gustavsson, Oliver Dorigo, Carolyn R. Bertozzi, W. E. Moerner

Developmental Cell 50(1) 57-+ (2019) | Journal

Physical Principles of Membrane Shape Regulation by the Glycocalyx

Carolyn R. Shurer, Joe Chin-Hun Kuo, LaDeidra Monet Roberts, Jay G. Gandhi, Marshall J. Colville, Thais A. Enoki, Hao Pan, Jin Su, Jade M. Noble, et al.

Cell 177(7) 1757-+ (2019) | Journal

Bisacylphosphane oxides as photo-latent cytotoxic agents and potential photo-latent anticancer drugs

Andreas Beil, Friederike A. Steudel, Christoph Braeuchle, Hansjorg Grutzmacher, Leonhard Möckl

Scientific Reports 9 6003 (2019) | Journal | PDF

Zur logischen Position der Hypothese

Leonhard Möckl

Vernunft und Leben aus transzendentaler Perspektive. Festschrift für Albert Mues zum 80. Geburtstag. 145-154 (2019)


2018

Von Kautschuk zu Metallen: ein Werkslabor mit Weltgeltung

Leonhard Möckl, Jürgen Evers, Christiane Herzog

Nachrichten aus der Chemie 66(9) 892-895 (2018) | Journal

Quantitative super-resolution microscopy reveals the architecture of the mammalian glycocalyx and its changes during cancer progression

Leonhard Möckl, Kayvon Pedram, Anish Roy, Anna-Karin Gustavsson, Carolyn Bertozzi, William Moerner

Abstracts of Papers of the American Chemical Society 256 320-ANYL (2018)

Invasiveness of Cells Leads to Changes in Their Interaction Behavior with the Glycocalyx

Ellen Broda, Adriano A. Torrano, Laura Loebbert, Leonhard Möckl, Christoph Braeuchle, Hanna Engelke

Advanced Biosystems 2(8) 1800083 (2018) | Journal

Quantitative Super-Resolution Imaging Reveals Mammalian Glycocalyx Dynamics

Leonhard Möckl, Kayvon Pedram, Anish Roy, Carolyn Bertozzi, William Esco Moerner

Biophysical Journal 114(3) 537A-538A (2018)

Die neue Macht des Forschers

Leonhard Möckl

Nachrichten aus der Chemie 66(2) 103-103 (2018) | Journal


2017

Dendrimer-Based Signal Amplification of Click-Labelled DNA in Situ

Nada Raddaoui, Samuele Stazzoni, Leonhard Möckl, Bastien Viverge, Florian Geiger, Hanna Engelke, Christoph Braeuchle, Thomas Carell

ChemBioChem 18(17) 1716-1720 (2017) | Journal

Azido Pentoses: A New Tool To Efficiently Label Mycobacterium tuberculosis Clinical Isolates

Katharina Kolbe, Leonhard Möckl, Victoria Sohst, Julius Brandenburg, Regina Engel, Sven Malm, Christoph Braeuchle, Otto Holst, Thisbe K. Lindhorst, et al.

ChemBioChem 18 SI(13) 1172-1176 (2017) | Journal

Back Cover: Azido Pentoses: A New Tool To Efficiently Label Mycobacterium tuberculosis Clinical Isolates (ChemBioChem 13/2017)

Katharina Kolbe, Leonhard Möckl, Victoria Sohst, Julius Brandenburg, Regina Engel, Sven Malm, Christoph Bräuchle, Otto Holst, Thisbe K. Lindhorst, et al.

Chembiochem 18(13) 1172-1172 (2017) | Journal

New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Magdalena Vater, Leonhard Möckl, Vanessa Gormanns, Carsten Schultz Fademrecht, Anna M. Mallmann, Karolina Ziegart-Sadowska, Monika Zaba, Marie L. Frevert, Christoph Braeuchle, et al.

Scientific Reports 7 44277 (2017) | Journal | PDF

The Endothelial Glycocalyx Controls Interactions of Quantum Dots with the Endothelium and Their Translocation across the Blood-Tissue Border

Bernd Uhl, Stephanie Hirn, Roland Immler, Karina Mildner, Leonhard Möckl, Markus Sperandio, Christoph Braeuchle, Christoph A. Reichel, Dagmar Zeuschner, et al.

ACS Nano 11(2) 1498-1508 (2017) | Journal

The glycocalyx regulates the uptake of nanoparticles by human endothelial cells in vitro

Leonhard Möckl, Stephanie Hirn, Adriano A. Torrano, Bernd Uhl, Christoph Braeuchle, Fritz Krombach

Nanomedicine 12(3) 207-217 (2017) | Journal

More Than 50 Years after Its Discovery in SiO2 Octahedral Coordination Has Also Been Established in SiS2 at High Pressure

Juergen Evers, Leonhard Möckl, Gilbert Oehlinger, Ralf Koeppe, Hansgeorg Schnoeckel, Oleg Barkalov, Sergey Medvedev, Pavel Naumov

Inorganic Chemistry 56(1) 372-377 (2017) | Journal


2016

100 Jahre Einkristallzucht aus der Schmelze: Vom Spreeknie ins Silicon Valley

Jürgen Evers, Christiane Herzog, Leonhard Möckl, Christoph von Plotho, Peter Stallhofer, Rudolf Staudigl

Chemie in unserer Zeit 50(6) 410-419 (2016) | Journal

En route from artificial to natural: Evaluation of inhibitors of mannose-specific adhesion of E. coli under flow

Leonhard Möckl, Claudia Fessele, Guillaume Despras, Christoph Braeuchle, Thisbe K. Lindhorst

Biochimica et Biophysica Acta-General Subjects 1860(9) 2031-2036 (2016) | Journal

En route from artificial to natural: Evaluation of inhibitors of mannose-specific adhesion of E. coli under flow General subjects

Leonhard Möckl, Claudia Fessele, Guillaume Despras, Christoph Bräuchle, Thisbe K. Lindhorst

Biochimica et Biophysica Acta (BBA) - General Subjects 1860(9) 2031-2036 (2016) | Journal

Inside Cover: Artificial Formation and Tuning of Glycoprotein Networks on Live Cell Membranes: A Single‐Molecule Tracking Study (ChemPhysChem 6/2016)

Leonhard Möckl, Thisbe K. Lindhorst, Christoph Bräuchle

ChemPhysChem 17(6) 779-779 (2016) | Journal

Artificial Formation and Tuning of Glycoprotein Networks on Live Cell Membranes: A Single-Molecule Tracking Study

Leonhard Möckl, Thisbe K. Lindhorst, Christoph Braeuchle

ChemPhysChem 17(6) 829-835 (2016) | Journal

Switching first contact: photocontrol of E. coli adhesion to human cells

Leonhard Möckl, A. Mueller, C. Braeuchle, T. K. Lindhorst

Chemical Communications 52(6) 1254-1257 (2016) | Journal | PDF


2015

Microdomain Formation Controls Spatiotemporal Dynamics of Cell-Surface Glycoproteins

Leonhard Möckl, Andrea K. Horst, Katharina Kolbe, Thisbe K. Lindhorst, Christoph Braeuchle

ChemBioChem 16(14) 2023-2028 (2015) | Journal

Inside Cover: Microdomain Formation Controls Spatiotemporal Dynamics of Cell‐Surface Glycoproteins (ChemBioChem 14/2015)

Leonhard Möckl, Andrea K. Horst, Katharina Kolbe, Thisbe Lindhorst, Christoph Bräuchle

Chembiochem 16(14) 1966-1966 (2015) | Journal

Wichard von Moellendorff: Mit logischer Schärfe und systematischer Unbeugsamkeit

Jürgen Evers, Leonhard Möckl

Chemie in unserer Zeit 49(4) 236-247 (2015) | Journal

Two High-Pressure Phases of SiS2 as Missing Links between the Extremes of Only Edge-Sharing and Only Corner-Sharing Tetrahedra

Juergen Evers, Peter Mayer, Leonhard Möckl, Gilbert Oehlinger, Ralf Koeppe, Hansgeorg Schnoeckel

Inorganic Chemistry 54(4) 1240-1253 (2015) | Journal

Cell-Penetrating and Neurotargeting Dendritic siRNA Nanostructures

Korbinian Brunner, Johannes Harder, Tobias Halbach, Julian Willibald, Fabio Spada, Felix Gnerlich, Konstantin Sparrer, Andreas Beil, Leonhard Möckl, et al.

Angewandte Chemie - International Edition 54(6) 1946-1949 (2015) | Journal

Dendritische Nanostrukturen zur rezeptorvermittelten Aufnahme von siRNA in neurale Zellen

Korbinian Brunner, Johannes Harder, Tobias Halbach, Julian Willibald, Fabio Spada, Felix Gnerlich, Konstantin Sparrer, Andreas Beil, Leonhard Möckl, et al.

Angewandte Chemie 127(6) 1968-1971 (2015) | Journal


2014

Super-resolved Fluorescence Microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner

Leonhard Möckl, Don C. Lamb, Christoph Braeuchle

Angewandte Chemie - International Edition 53(51) 13972-13977 (2014) | Journal


2012

Der Wittelsbacher und der Hope‐Diamant: Optische Untersuchungen klären ein Rätsel

Jürgen Evers, Leonhard Möckl, Heinrich Nöth

Chemie in unserer Zeit 46(6) 356-364 (2012) | Journal

Optical Investigations to clear up a Mystery The Wittelsbach and the Hope Diamond

Juergen Evers, Leonhard Möckl, Heinrich Noeth

Chemie in unserer Zeit 46(6) 356-364 (2012) | Journal

Tuning Nanoparticle Uptake: Live-Cell Imaging Reveals Two Distinct Endocytosis Mechanisms Mediated by Natural and Artificial EGFR Targeting Ligand

Frauke M. Mickler, Leonhard Möckl, Nadia Ruthardt, Manfred Ogris, Ernst Wagner, Christoph Braeuchle

Nano Letters 12(7) 3417-3423 (2012) | Journal

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