Cornelia Holler, M.Sc.

  • Doctoral Student
  • Room: A.3.242
  • Telephone: +49 9131 7133342
  • E-mail

In my studies, I am using interferometric scattering microscopy for tracking the mobility of single proteins in order to reveal and characterize nanoscale interactions with and dynamics within the plasma membrane of living cells. Revealing these dynamics grants insights into diseases associated with altered membrane organization and function. In addition, I am interested in developing nanofluidic-based research tools for innovative single-cell studies combined with advanced microscopy techniques.

A paintbrush for delivery of nanoparticles and molecules to live cells with precise spatiotemporal control

Cornelia Holler, Richard W. Taylor, Alexandra Schambony, Leonhard Möckl, Vahid Sandoghdar

Nature Methods 21 512-520 (2024) | Journal

High-precision protein-tracking with interferometric scattering microscopy

Richard W. Taylor, Cornelia Holler, Reza Gholami Mahmoodabadi, Michelle Küppers, Houman Mirzaalian Dastjerdi, Vasily Zaburdaev, Alexandra Schambony, Vahid Sandoghdar

Frontiers in Cell and Developmental Biology 8 590158 (2020) | Journal

I was born in Germany where I completed a Bachelors program in Biology in 2015, followed by a Masters program on “Cell and molecular biology” in 2018, both at the Friedrich-Alexander-University in Erlangen. For my Masters work I was awarded the “Fritz und Maria Hofmann-Preis”and the “Masterpreis of the Department Biology”, respectively.

In 2019, I started my doctoral studies at the Max Planck Institute for the Science of Light in Erlangen in the group of Prof. Dr. Vahid Sandoghdar. In my work, I focus on interferometric scattering-based particle tracking on living cells. In addition, I am also developing nanofluidic research tools to enable new avenues for single-cell investigations with advanced microscopy techniques.

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