Nano-Optics

Division Vahid Sandoghdar

Welcome to the Nano-Optics Division

The nano-optics division at MPL strives to advance experimental and theoretical mastery of light-matter interaction at the nanometer scale. We deal with objects on the scales of single molecules, proteins or viruses. Our research portfolio encompasses a wide spectrum of scientific questions with the emphasis currently on the two key areas of nano-quantum-optics and nano-bio-photonics. A feature common to our research fields is that they typically address the condensed phase with a considerable degree of complexity.

Our research group takes up the challenge of designing projects and developing measurement strategies enabling a quantitative understanding of these complex systems in an elegant manner. The group was originally founded in 1997 at the University of Konstanz, where we pioneered the combination of concepts from quantum optics, laser spectroscopy, cryogenics, optical imaging, nanotechnology, and scanning probe technology. After ten productive years of research at ETH Zurich, we moved to MPL in Erlangen in 2011.

In September 2017, we organized a symposium to celebrate 20 years of nano-optics as an overarching research area dedicated to the interaction of light and matter at the nanometer scale. At this event, we interviewed sixteen pioneers who contributed to the development of the field. We have created a video highlighting how nano-optics emerged as a field and what its future challenges might be (click here to watch the video). The individual interviews are also available via our institute video depository.

Nano-Quantum-Optics

Over two decades of investigating fundamental optical processes at the single photon and single emitter level, we have pioneered the demonstration of efficient coupling between light and single quantum emitters without the need for cavities or antennas. We also demonstrated one of the very first and most quantitative cases of radiative enhancement by a plasmonic nanoantenna. Most of our work concerns solid-state samples and single organic molecules, however our findings are often generalizable to other systems such as atoms, ions, quantum dots, or color centers.  Currently, our group is concerned with the realization of a controlled number of interacting quantum emitters, photons and phonons.

 

 

Nano-Bio-Photonics

In our nano-bio-photonics branch, we exploit our expertise to perform novel forms of microscopy and to develop platforms for controlled experiments in the area of biophysics and fundamental medical research. Here, we are particularly interested in quantitative understanding of the interaction between individual viruses, vesicles and proteins with cells and tissues. Two important techniques developed in our lab are

1) interferometric scattering (iSCAT) microscopy and
2) cryogenic super-resolution microscopy.

We collaborate with many biologists, biophysicists and physicians around the world.
For more information, please see our publications list and the highlights section of this website.

 

Contact

Nano-Optics Division
Prof. Vahid Sandoghdar

Max Planck Institute for the Science of Light
Staudtstr. 2
91058 Erlangen, Germany

vahid.sandoghdar@mpl.mpg.de

+49 9131 7133 300


Max-Planck-Zentrum für Physik und Medizin
Kussmaulallee 2
91054 Erlangen, Germany

vahid.sandoghdar@mpzpm.mpg.de

Director Professor Vahid Sandoghdar

Berthold Leibinger Innovation Prize

Team around Prof. Vahid Sandoghdar wins Berthold Leibinger Innovation Prize

Prof. Vahid Sandoghdar, Director at the Max Planck Institute for the Science of Light (MPL), and his team receive the first prize of the Berthold Leibinger Innovation Prize on Friday, June 20, 2025, for the development of the novel analysis method iNTA (interferometric nanoparticle tracking analysis). The award is presented every two years for outstanding projects in the field of innovative…

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iNTA - Interferometric Nanoparticle Tracking Analysis

The Berthold Leibinger Stiftung visited us to create a film portrait of the iNTA team, showcasing our innovative research.

Characterization of the size and material properties of nanoparticles in liquid suspensions is in very high demand, e.g., in the analysis of bodily fluids such as urine and blood plasma or of medication samples such as vaccines. iNTA is a new method that combines…

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Advancing cryogenic light microscopy

Two recent papers published in PNAS and Science Advances introduce powerful new approaches in cryogenic light microscopy. The work enables angstrom-level localization precision and provides quantitative insights into protein conformations in their native cellular environment — opening new possibilities for structural biology and high-resolution imaging.

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Hybridization of molecules via a common photonic mode

PNAS

Atoms and molecules usually hybridize and form bonds when they come in very close proximity of each other. In this work, we show that molecules can hybridize even through far-field electromagnetic interactions mediated by the shared mode of an optical microcavity. We discuss a collective enhancement of the vacuum Rabi splitting and study super- and subradiant states that arise from the…

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nature reviews methods primers

Interferometric scattering microscopy

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Interview with Vahid Sandoghdar

at IFIMAC – Condensed Matter Physics Center, Universidad Autónoma de Madrid

IFIMAC PhD students Beatriz Viña, Anna-Luisa Römling, Diego Fernández and Jose Antonio Moreno interviewed Vahid Sandoghdar. Diego also talked to Vahid about his research and his personal experiences during his career in basic research.

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Essay

Exploring the Physics of Basic Medical Research

The 20th century witnessed the emergence of many paradigm-shifting technologies from the physics community, which have revolutionized medical diagnostics and patient care. However, fundamental medical research has been mostly guided by methods from areas such as cell biology, biochemistry, and genetics, with fairly small contributions from physicists. In this Essay, I outline some key…

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