Dr. Alexandra Schambony

  • Senior Scientist
  • Room: A.3.240
  • Telephone: +49 9131 7133339
  • E-mail

Proteins constitute the functionalities of each individual cell. During their lifetime, proteins are constantly in motion; either freely diffusing in the cytoplasm or within cell membranes or being actively transported between cell organelles and functional phases. I am interested in analyzing and understanding diffusion and transport of proteins in living cells by tracking single-particles via iSCAT imaging.

Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane

Richard W. Taylor, Reza Gholami Mahmoodabadi, Verena Rauschenberger, Andreas Giessl, Alexandra Schambony, Vahid Sandoghdar

Nature Photonics 13 480-487 (2019) | Journal

High-precision protein-tracking with interferometric scattering microscopy

Richard W. Taylor, Cornelia Holler, Reza Gholami Mahmoodabadi, Michelle Küppers, Houman Mirzaalian Dastjerdi, Vasily Zaburdaev, Alexandra Schambony, Vahid Sandoghdar

Frontiers in Cell and Developmental Biology 8 590158 (2020) | Journal

A paintbrush for delivery of nanoparticles and molecules to live cells with precise spatiotemporal control

Cornelia Holler, Richard W. Taylor, Alexandra Schambony, Leonhard Möckl, Vahid Sandoghdar

Nature Methods 2024 (2024)

MPL Shop

The World of Light to Touch and Wear.

Shop now!

MPL Research Centers and Schools