Dr. Alexandra Schambony

  • Senior Scientist
  • Room: A.3.240
  • Telephone: +49 9131 7133339
  • E-mail

Proteins constitute the functionalities of each individual cell. During their lifetime, proteins are constantly in motion; either freely diffusing in the cytoplasm or within cell membranes or being actively transported between cell organelles and functional phases. I am interested in analyzing and understanding diffusion and transport of proteins in living cells by tracking single-particles via iSCAT imaging.

Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane

Richard W. Taylor, Reza Gholami Mahmoodabadi, Verena Rauschenberger, Andreas Giessl, Alexandra Schambony, Vahid Sandoghdar

Nature Photonics 13 480-487 (2019) | Journal


High-precision protein-tracking with interferometric scattering microscopy

Richard W. Taylor, Cornelia Holler, Reza Gholami Mahmoodabadi, Michelle Küppers, Houman Mirzaalian Dastjerdi, Vasily Zaburdaev, Alexandra Schambony, Vahid Sandoghdar

Frontiers in Cell and Developmental Biology 8 590158 (2020) | Journal


A paintbrush for delivery of nanoparticles and molecules to live cells with precise spatiotemporal control

Cornelia Holler, Richard W. Taylor, Alexandra Schambony, Leonhard Möckl, Vahid Sandoghdar

Nature Methods 2024 (2024)


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