Welcome to the website of Biological Optomechanics Division

Cells are the basic entities of biological systems. They have particular physical properties, which enable them to navigate their 3D physical environment and fulfill their biological functions. We investigate these physical – mechanical and optical – properties of living cells and tissues using novel photonics and biophysical tools to test their biological importance. Our ultimate goal is the transfer of our findings to medical application in the fields of improved diagnosis of diseases and novel approaches in regenerative medicine.


Rosalind Elsie Franklin looking through a microscope

New scholarship of MPZPM for outstanding scientists

In memory of the pioneering English chemist Rosalind Franklin, the Max-Planck-Zentrum für Physik und Medizin has set up a scientist-in-residence...

Read more
Diluting of a blood sample.

How a corona infection changes blood cells in the long run

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first...

Read more

Horizon Award for Leonhard Möckl

The British Royal Society of Chemistry has awarded a research team for their work on the protective sugar coat of cells, which included the scientist...

Read more

Cell Mechanics

Mechanical properties of cells are very often connected to their state and function. They can thus serve as an intrinsic biophysical marker of cell state transitions, such as metastasis of cancer cells, activation of leukocytes, or progression through the cell cycle. Read More...

Mechanosensing

Cells actively sense and respond to a variety of mechanical signals — a process known as mechanosensing. Mechanical cues provided by the extracellular environment can modulate a wide spectrum of cellular events, including cell proliferation, differentiation and protein production. Read More...

Tissue Mechanics

Cells define and largely form their surrounding tissues and, in return, receive biochemical and physical cues from them. We are working on resolving this interdependence by quantifying these tissue mechanical properties, correlating them with biological function, investigating their origin and ultimately controlling them. Read More...

Biophotonics

Biophotonics describes the interaction of light with cells and tissues. We are interested in the interaction between light and tissues which is governed by the optical properties of cells. Read More...

Physical phenotype of blood cells is altered in COVID-19

Markéta Kubánková, Bettina Hohberger, Jakob Hoffmanns, Julia Fürst, Martin Herrmann, Jochen Guck, Martin Kräter

Biophysical Journal 120(14) 2838-2847 (2021) | Journal | PDF

HIF2α is a Direct Regulator of Neutrophil Motility

Sundary Sormendi, Mathieu Deygas, Anupam Sinha, Anja Krüger, Ioannis Kourtzelis, Gregoire Le Lay, Mathilde Bernard, Pablo J. Sáez, Michael Gerlach, et al.

Blood 137(24) 3416-3427 (2021) | Journal | PDF

Rapid computational cell-rotation around arbitrary axes in 3D with multi-core fiber

Jiawei Sun, Nektarios Koukourakis, Jochen Guck, Jürgen W. Czarske

Biomedical Optics Express 12(6) 3423-3437 (2021) | Journal | PDF

Contact

For all general inquiries, please contact us at:

Guck Division
Max Planck Institute for the Science of Light
Staudtstr. 2
D-91058 Erlangen, Germany

guck-office@mpl.mpg.de

Tel: +49-9131-7133-501
Fax: +49-9131-7133-990

The Max Planck Institute is located right next to the Science Campus of the Friedrich-Alexander-University Erlangen-Nuremberg, on its northern edge. See the information page on how to find us.

MPL Newsletter

Stay up-to-date with MPL’s latest research via our Newsletter. 

Current issue: Newsletter No 16 - February 2021

Click here to view previous issues.

MPL Research Centers and Schools